Four-time champion and world number one Djokovic hit 13 aces and 37 winners as he eased past Denis Kudla of the United States, 6-3, 6-2, 6-2. "I'm pleased with my game overall. There were some moments in the match where maybe I could have done better," said the defending champion. "But overall, a solid performance." Djokovic goes on to face Hubert Hurkacz for a place in the last 16 having defeated the Pole in straight sets in the first round at Roland Garros in May.
Victory in that match could see him face 18-year-old Canadian Felix Auger-Aliassime, the youngest man in the draw. The 19th seed saw off French qualifier Corentin Moutet 6-3, 4-6, 6-4, 6-2 to make the third round of a Slam for the first time. Last year's beaten finalist Kevin Anderson, the South African fourth seed, also progressed with a 6-4, 6-7 (5/7), 6-1, 6-4 victory over Janko Tipsarevic of Serbia.
Three-time major winner Stan Wawrinka fell in five sets to 6ft 11in (2.1m) Reilly Opelka. Two-time quarter-finalist Wawrinka, 34, was beaten 7-5, 3-6, 4-6, 6-4, 8-6 by his American opponent, the tallest man in the sport and 13 years his junior.